Endocannabinoids in cerebrovascular regulation
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چکیده
منابع مشابه
Endocannabinoids in cerebrovascular regulation.
The cerebral blood flow is tightly regulated by myogenic, endothelial, metabolic, and neural mechanisms under physiological conditions, and a large body of recent evidence indicates that inflammatory pathways have a major influence on the cerebral blood perfusion in certain central nervous system disorders, like hemorrhagic and ischemic stroke, traumatic brain injury, and vascular dementia. All...
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In mammals, including humans, bone metabolism is manifested as an ongoing modelling/remodelling process whereby the bone mineralised matrix is being continuously renewed. Recently, the main components of the endocannabinoid system have been reported in the skeleton. Osteoblasts, the bone forming cells, and other cells of the osteoblastic lineage, as well as osteoclasts, the bone resorbing cells...
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The cerebrovasculature dilates or constricts in response to acute blood pressure changes to stabilize cerebral blood flow across a range of blood pressures. It is unclear, however, whether such dynamic cerebral autoregulation (dCA) is equally effective in responding to falling versus rising blood pressure. In this study we applied a pharmacological approach to evaluate dCA gain to transient hyp...
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into two parts-one was retained for bacteriological examination and the other dispatched frozen to the Torry Research Station at Aberdeen for chemical analysis. The total bacterial count was less than 500 organisms/g, consisting largely of coagulase-negative staphylococci. The Torry Research Station reported that the fish seemed in good condition but was very lightly cured (salt/wet weight 0-9 ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2016
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00571.2015